药物建议委员会审议结果

DAC Meeting Outcome - Apr 2024

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The HA Drug Advisory Committee (DAC), comprising doctors, clinical pharmacologists and pharmacists, systematically appraises new drugs every three months. DAC is supported by expert panels which provide specialist views on the selection of drugs for individual specialties.

Drug Advisory Committee April 2024 Meeting Outcome

 

Generic name

Brand name

Therapeutic Class

Meeting outcome

Primary reason for rejection1

1

Adalimumab

Amgevita

Gastro-intestinal system

Approved

 

2

Atezolizumab

Tecentriq

Malignant disease and immunosuppression

Approved

 

3

Bempedoic acid

Nilemdo

Cardiovascular system

Rejected

Alternative(s) available in HADF with comparable benefits

4

Dostarlimab

Jemperli

Malignant disease and immunosuppression

Approved

 

5

Fluticasone/Umeclidinium/Vilanterol

Trelegy Ellipta

Respiratory system

Pending

Pending further information

6

Glycerol phenylbutyrate

Ravicti

Nutrition and blood

Rejected

The justification of the treatment’s cost in relation to its benefits is insufficient

7

Golimumab

Simponi

Musculoskeletal and joint disease

Pending

Pending further information

8

Insulin glargine

Toujeo

Endocrine system

Approved

 

9

Lemborexant

Dayvigo

Central nervous system

Rejected

Insufficient evidence of long-term safety

10

Lenalidomide

Revlimid

Malignant disease and immunosuppression

Approved

 

11

Lutetium 177 vipivotide tetraxetan 

Pluvicto

Radiopharmaceuticals

Pending

Pending further information

12

Nivolumab 

Opdivo

Malignant disease and immunosuppression

Rejected

Insufficient evidence of long-term clinical outcome benefits / The justification of the treatment’s cost in relation to its benefits is insufficient

13

Nivolumab / Ipilimumab

Opdivo/ Yervoy

Malignant disease and immunosuppression

Approved

 

14

Pembrolizumab

Keytruda

Malignant disease and immunosuppression

Approved

 

15

Pembrolizumab / Axitinib

Keytruda/ Inlyta

Malignant disease and immunosuppression

Rejected

The justification of the treatment’s cost in relation to its benefits is insufficient

16

Safinamide

Equfina

Central nervous system

Rejected

Insufficient comparative studies versus existing treatment

17

Trastuzumab Deruxtecan

Enhertu

Malignant disease and immunosuppression

Approved

 

18

Upadacitinib

Rinvoq

Gastro-intestinal system

Rejected

The justification of the treatment’s cost in relation to its benefits is insufficient

19

Vedolizumab

Entyvio

Gastro-intestinal system

Rejected

Insufficient evidence to demonstrate significant clinical outcome benefits

1 The evaluation embraces the principles of safety, efficacy and cost-effectiveness and takes into account other relevant factors, including international recommendations and practices, advance in technology, disease state, patient compliance, quality of life, actual experience in the use of drugs as well as views of professionals and patients groups.